Please Visit Our New Website

The Brain Science Podcast and Blog website has moved to http://docartemis.com/brainsciencepodcast/. Within a few hours http://brainsciencepodcast.com should also point to the new site. This move will allow me greater control over the site’s content. The old site at http://brainsciencpodcast.wordpress.com will be maintained only as an archive for old show notes and blog posts. Please make sure you update your book marks. Check your RSS feed also. If it pointed at http://feeds.feedburner.com/brainsciencepodcast you don’t have to do anything, but if you are subcribed to http://brainsciencpodcast.wordpress.com/feed/ you will need to change to the Feedburner feed.

I would appreciate your feedback on the new site.

Brain Science Podcast #39: Michael Arbib on Mirror Neurons

Episode 39 of the Brain Science Podcast is an interview with Dr. Michael Arbib from the University of Southern California. Dr. Arbib’s work with functional brain imaging has established the presence of mirror neurons in the human brain. In our interview we focused on the role of mirror neurons in imitation and language. In particular I questioned Dr. Arbib about the Mirror System Hypothesis (MSH) of Language Evolution that he proposed in 1998 with Giacomo Rizzolatti. We also explored how this hypothesis diverges from the universal grammar proposed by Noam Chomsky. Dr. Arbib also shared his enthusiasm for future research and we talked about the special challenges caused by the interdisciplinary nature of modern neuroscience.

Listen to the Interview

Related Episodes:

• Brain Science Podcast #7: A discussion of bonobos with Stuart Shanker, PhD
• Brain Science Podcast #30: a discussion of language evolution including my thoughts on Chomsky
• Brain Science Podcast #35: a detailed discussion of Mirrors in the Brain by Giacomo Rizzolatti

Scientists Mentioned in the Interview:

• Giacomo Rizzolatti: His team discovered mirror neurons at the University of Parma, Italy
• Other team members: Vittorio Gallese, Luciano Fadiga, and Leo Fogassi
• Ursula Bellugi (Salk Institute): pioneered the neurobiology of sign language
• Richard Byrne (University of St. Andrews): studies how gorillas learn in the wild
• Michael Tomasello (Max Planck Institute for Comparative Anthropology): studies social behavior of primates, including how communicative gestures vary between groups.
• Noam Chomsky (MIT): famous linguist who has proposed an inborn universal grammar
• DL Cheney and RM Seyfarth: research about primate vocal behavior, especially the use of calls in the wild.

References:

• Cybernetics, by Norbert Wiener- this classic inspired Dr. Arbib’s career in computational neuroscience.
• Action to Language via the Mirror Neuron System, (2006) edited by Michael Arbib.
• Mirrors in the Brain by Giacomo Rizzolatti and Corrado Sinigaglia, 2008. Discussed in Episode 37.
• Mirroring People by Marco Iacoboni, 2008. The author studies mirror neurons at UCLA.
• Rizzolatti G & Arbib MA Language within our grasp. Trends in Neuroscience 21(5): 188-194- the first paper describing the Mirror System Hypothesis, 1998.
• Iacoboni M, Molnar-Szakacs I, Gallese V, Buccino G, Mazziotta JC, et al. Grasping the intentions of others with one’s own mirror neuron system. PLoS Biol 3 (3): e79, 2005.
• Arbib, M.A., “From Monkey-like Action Recognition to Human Language: An Evolutionary Framework for Neurolinguistics” (with commentaries and author’s response), Behavioral and Brain Sciences, 28:105-167. (Click here for supplemental commentaries and the author’s “electronic response.”) 2005.
• Arbib MA 2006 “Broca’s Area in System Perspective: Language in the Context of Action-Oriented Perception” in Broca’s Region, Oxford University Press, pp 153-168.
• Arbib MA 2008 “Invention and Community in the Emergence of Language: Insights from New Sign Languages,” in Foundations in Evolutionary Cognitive Neuroscience, Cambridge University Press.
• Click here for more papers by Dr. Arbib. He has also written over 40 books.

Other Links:

• Michael Arbib’s website

Listen to Episode 39 of the Brain Science Podcast

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Brain Science Podcast #37: Dr. John Medina discusses “Brain Rules”

John Medina, PhD

Episode 37 of the Brain Science Podcast is an interview with Dr. John Medina, author of Brain Rules: 12 Principles for Surviving and Thriving at Work, Home, and School. We talk about how exercise, sleep, and stress effect our brains with an emphasis on practical advice for healthier brain function. We also look at how research on memory, vision and the brain’s attention system suggests how we can improve our ability to learn and our ability to share ideas with others.

Dr. Medina’s focus is on considering real world examples of how our schools and work environments could be reformed to utilize the growing knowledge of neuroscience. But he also stresses the importance of compiling sufficient experimental data before embarking on new programs.

Listen to Episode 37 now (left click to listen, right click to download mp3).

Links and References:

Brain Rules: 12 Principles for Surviving and Thriving at Work, Home, and School (Book & DVD) by John Medina

The book’s website contain extensive references and instructive videos.

YouTube Video of John Medina speaking at Google™.

Listen to Brain Science Podcast #37

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Brain Science Podcast #36: Art Glenberg on Embodied Cognition

Art Glenberg, PhD

Episode 36 of the Brain Science Podcast is an interview with Arthur Glenberg, PhD about embodied cognition. Dr. Glenberg recently moved to Arizona State University after over 30 years at the University of Wisconsin’s Laboratory of Embodied Cognition. His research focuses on the relationship between embodiment and language. In this interview we explore the experimental evidence for a theory of language that embraces the concept that our language abilities are actually rooted in our perceptual and motor abilities. Dr. Glenberg also explains how his work has practical implications in helping children learn how to read.

Since Dr. Glenberg has had a long career as a working research scientist, this interview also provided an opportunity to explore how scientific hypotheses are formed and how experiments are designed to test these hypothesis. I think this interview will give you a fascinating look into the real world of cognitive psychology.

Listen to Dr. Glenberg’s Interview (left click to listen, right click to download)

Links and References:

Arthur Glenberg, PhD

• email: arthur.glenberg@asu.edu
• Laboratory for Embodied Cognition
• Havas, D.A., Glenberg, A.M., and Rink, M. (2007) Emotion simulation during language comprehension. Psychonomic Bulletin & Review 14 (3), 436-441
• Numerous references available as PDF
• Thinking With the Body: blog post of March 3, 2008

Other Scientists Mentioned in the Episode:

• George Lakoff: pioneering linguist
• James Gibson-known for his ideas about affordances
• William Epstein-emeritus professor at the University of Wisconsin
• Joseph Campos: University of California (Berkelely)
• Amy Needham and Amanda Woodard-experiments with velcro mits and infant cognition
• David A Havas: graduate student and co-author with Dr. Glenberg
• Mike Kashak: Florida State University
• Mike Rinck: German co-author-see paper under Glenberg (more papers)
• Vittorio Gallese, Dept of Neuroscience, University of Parma, Italy (where mirror neurons were discovered): extensive experimental with motor neurons in monkeys
• Fritz Stack (Germany): experiments showing that facial experiments affect mood and cognition

References:

• Havas, D.A., Glenberg, A.M., and Rink, M. (2007) Emotion simulation during language comprehension. Psychonomic Bulletin & Review 14 (3), 436-441
• more publications by Arthur Glenberg
• Sommerville, J.A., Woodard, A.L., and Needham, A., Action experience alters 3-month-old infants’ perception of others’ actions, Cognition 96 (2005) B1-B11.
• Strack, F., Martin, L. L., & Stepper, S. (1988). Inhibiting and facilitating conditions of the human smile: A nonobtrusive test of the facial feedback hypothesis. Journal of Personality & Social Psychology, 54, 768-777.
• Women, Fire, and Dangerous Things (1987) by George Lakoff
• recent essays by George Lakoff written for the Rockridge Institute

Listen to Dr. Glenberg’s Interview (left click to listen, right click to download)

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Transcript of György Buzsáki’s Interview is now On-line

Episode 31 of the Brain Science Podcast was a challenging interview with György Buzsáki about his book Rhythms of the Brain. Thanks to listener Diane Jacobs we now have a transcript available for Episode 31.

Click here for the transcript.

Be sure to visit Diane’s Blog at http://humanantigravitysuit.blogspot.com/. When it comes to reading books about neuroscience, Diane makes me feel like a slacker.

Brain Science Podcast #35: A Closer Look at Mirror Neurons

Brain Science Podcast #35 is a discussion of Mirrors in the brain: How our minds share actions, emotions, and experience by Giacomo Rizzolatti and Corrado Sinigaglia. Mirror neurons were discovered in Rizzolatti’s lab in Parma Italy in the early 1990′s and his book is a detailed to discussion of the experimental evidence in both monkeys and humans. Direct single neuron recordings have been made in monkeys. The evidence in humans is indirect since it is based on mainly on neuroimaging studies like PET scans and fMRI scans. Even so mirror neurons appear to be essential to our ability to understand both the actions and emotions of others. Listen Now.

In this episode we also explore the evidence that there are other neurons in the motor areas of the brain that have sensory properties and that the areas of the brain traditionally thought to be devoted to sensory functions also contain neurons with motor properties. Another fascinating discovery is the fact that there are neurons that respond not only to somatosensory inputs (such as being touched) but also to visual or auditory inputs from objects within our peri-personal space. For background on these body maps I recommend listening to Episode 21 and Episode 23. If you are new to the Brain Science Podcast you may want to listen to those episodes first because this week’s episode is a little more technical than most.

I will be exploring the importance of these discoveries in future episodes.

Listen to Brain Science Science Podcast Episode 35 (mirror neurons) NOW.

Links:

Giacomo Rizzolatti- University of Parma

Mirror neurons (wikipedia entry)

Mirror neurons (Scholarpedia entry written by Dr. Rizzolatti)

Listen to Brain Science Podcast #35 (mirror neurons) Now

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Dan Rathers Reports on Neuroplasticity

Today HDNet™ is reshowing an episode of Dan Rather Reports called “Mind Science.” It is an excellent review of neuroplasticity. It includes interviews with several leading scientists in the field. I especially enjoyed seeing Nobel Laureate Eric Kandel talk about his work with memory. (I talked about Kandel’s work on the Brain Science Podcast in Episode 3 and Episode 12.)

“Mind Science” also features the Dalai Llama and scientist Richard Davidson talking about the evidence that meditation can change the brain. Rather interviews Sharon Begely about her book Train Your Mind, Change Your Brain: How a New Science Reveals Our Extraordinary Potential to Transform Ourselves (which I discussed in detail in Episode 10 of the Brain Science Podcast). Other scientists featured in the episode include Michael Merzenich on improving brain function as we age and Dr. Edward Taub on his revolutionary approach to stroke rehabilitation. (My show notes for Episode 10 include links for all the scientists interviewed by Rather.)

It was particulary gratifying to see Dr. Kandel endorse Ed Taub’s Constraint-Induced Movement Therapy. Dr. Taub was interviewed in Episode 28 of the Brain Science Podcast.

If you don’t get HDNet™ you can watch Dan Rather Reports on-line, via podcast or on Facebook.

Summary of relevant episodes of the Brain Science Podcast:

• Eric Kandel’s work on Memory: Episode 3 and Episode 12
• Neuroplasticity: Episode 10 and Episode 26
• Interview of Dr. Edward Taub: Episode 28

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More on BDNF: “Miracle Grow” for the Brain

In Episode 33 of the Brain Science Podcast, Harvard’s Dr. John Ratey introduced us to brain-derived neurotropic factor (BDNF), which he described as “Miracle Grow for the Brain” because it actually stimulates the grow of new neurons in the brain. The emphasis in our discussion was on the importance of exercise in stimulating the release of BDNF.

If you are interested in checking out some further references on BDNF you may want to check out Charles Daney’s Science and Reason Blog. Daney also does a good job of explaining exactly what a neurotropic factor is and does.

Treating Vets with Mirrors

Jamie Davis of Mediccast sent me a link to an interesting article from the CNN website. It describes how mirror box therapy is being used to help veterans who have suffered amputations in Iraq and Afghanistan. Those of you who heard Sandra Blakeslee’s interview about body maps back in Episode 23 will remember that she described how her son built the first mirror box for VS Ramachandran several years ago while working as a graduate student.

It is good to see that military physicians are beginning to apply some of the recent findings of neuroscience to helping injured vets, but you may also recall that when we talked with Dr. Edward Taub about stroke rehab, he reported the difficulty of getting new methods of head injury treatment into the VA clinics.

link to article about mirrors: http://www.cnn.com/2008/HEALTH/03/19/mirror.therapy/index.html 

Brain Science Podcast #34: Rachel Herz talks about Smell

Rachel Herz

Episode 34 of the Brain Science Podcast is an interview with Rachel Herz author of The Scent of Desire: Discovering Our Enigmatic Sense of Smell (2007). Dr. Herz teaches at Brown University and she is a leading authority on the psychology of smell. We talk about the how smell works, its role in emotion and memory, why it is so vulnerable, and why smell is much more important than most of us realize. We also consider some of the questions that remain unanswered.

Listen to the Rachel Herz interview now. (Right click to download.)

Links and References:

Rachel Herz

• Brown Medical School faculty page
• Wikipedia: a good source for further references
• RachelHerz.com
• thescentofdesire.com

The 2004 Nobel Prize for Medicine and Physiology was awarded to Richard Axel and Linda B. Buck for their discoveries of “odorant receptors and the organization of the olfactory system.”

BuckL, Axel R “A novel multigene family may encode odorant receptors: a molecular basis for odor recognition.”
Cell. 1991 Apr 5;65(1):175-87.

“The (Shocked) Nose Knows” by Gisela Telis ScienceNOW Daily News 27 March 2008

The Scent of Desire: Discovering Our Enigmatic Sense of Smell (2007) by Rachel Herz

Listen to Episode 34 (Right click to download)

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